CCS2000冷却系统设计用于冷藏并保持的代谢笼样品在或低于45华氏度(7摄氏度)。

产品由三部分组成：
1）15个MMC100小鼠代谢笼；
2）笼架；
3）冷却装置。
它是为我们的标准代谢笼和笼架而设计的，因此，它提供了所有hatteras产品相同的质量和功能保证。

使用要求:
尽管该系统是精心设计制作的，但是它的使用时很简单的。安装过程包括：将绝缘底座插入连接端口，将代谢笼放置到笼架上，给水槽中注水，和启动系统。就是这样。系统将自动开始制冷，以及维持与周围温度（室温）30度左右的温差。系统是可靠的和耐用的，不需要特殊的维护。

安装开始于制冷单元，制冷单元安装在笼架的底部，包含电子单元用来制冷和维持水的温度。还包括水槽，用来实现水循环。另外，该单元还包括一个控制器用来显示和控制温度水平。

笼架系统是一个支撑设施，包含铅管系统和制冷单元，作为代谢笼的连接点。笼架是铝质的，带有烤漆。3排水平结构，每个水平结构上带有5个小孔用来安装代谢笼。每一排的旁边的背板上是连接的端口，用来连接代谢笼的绝缘底座到铅管。制冷的绝缘底座为尿液样本提供制冷。笼子由丙烯酸零部件和不锈钢底板和独特设计的不锈钢收集漏斗组成。可以舒适的安全的连续24小时饲养一只小鼠，制冷的代谢笼提供和标准的代谢笼一样的收集能力。

产品优势:
冷却尿液样本将确保几个用于研究的好处:
1 保持样品的质量；
2 消除细菌繁殖；
3 维持一个稳定的pH值；
4 保持样本的活性；
此外，制冷过程可保持温暖环境气候中的笼内环境冷却，从而为老鼠提供更舒适的空气。

产品优势:
冷却尿液样本将确保几个用于研究的好处:
1 保持样品的质量；
2 消除细菌繁殖；
3 维持一个稳定的pH值；
4 保持样本的活性；
此外，制冷过程可保持温暖环境气候中的笼内环境冷却，从而为老鼠提供更舒适的空气。

KynurenineInfusion Disrupts Normal Blood Pressure Circadian Rhythms

DebraL IrsikW.BollagC.Isales

Biology, Medicine

The FASEB Journal   1 May 2022

The data suggest that kynurenine treatment impacts renalfunction and may contribute to the development of CKD, a significant riskfactor for cardiovascular disease, even in the context of normotension.

Changes inOxygen Consumption and Metabolomic Profiles in the Kidney of Sprague‐Dawley Rat fed a High‐Salt Diet

S.ShimadaBrianR. HoffmannAndrewS. GreeneMingyuLiangR.DashA.Cowley

Medicine, Biology

The FASEB Journal  1May 2022

It is concluded that a high‐salt diet increases oxygenconsumption and alters the metabolomic profiles of the kidney.

Toward the InterdisciplinaryTheory and Research

O.Yanitsky

Creative Education  6 March 2020

The article represents some thoughts and considerationson an interdisciplinary theory and research based on the relevant scientificworks and the author’s personal and “big family” experience and…

Toward theInterdisciplinary Theory and Research

AixaHafsha  19 April 2020

The article represents some thoughts and considerationson an interdisciplinary theory and research based on the relevant scientificworks and the author’s personal and “big family” experience and… 

High Salt DietIncreases Renal Oxygen Consumption in Sprague‐Dawley Rats

S.ShimadaR.DashA.Cowley

The FASEB Journal  1May 2021

It appears that in normal SD rats, the increased tubular metabolic workassociated with a high salt diet is initially accommodated by increasedperfusion (RBF) and a gradual increase of O2 consumption while extractionremains unchanged for a two‐week period.

Chronic RenalArtery Insulin Infusion Decreases 24 hr/day Renal Blood Flow in Diabetic Rats

M.BrandsW.Bush   Medicine, Biology

The FASEB Journal  1May 2021

A chronic renal vasoconstrictor influence of insulinunder diabetic conditions is suggested, which suggests that the decrease ininsulin may contribute directly to the renal vasodilation that occurs in type 1diabetes.

M.CrostelliO.MazzaM.MarianiD.MascelloC.Iorio

International Orthopaedics 14 September 2018

Bracing is a viable treatment strategy in thoracic lumbarkyphosis and can obtain good clinical results at medium terms follow-up even ifkyPHosis deformity remains in radiographs, as even smallest devices availableare often too big.

Precise Controlof Target Temperature Using N6-Cyclohexyladenosine and Real-Time Control ofSurface Temperature.

B.LaughlinI.BaileyS.RiceZ.BaratiLoriK. BogrenK.Drew

Therapeutic Hypothermia and Temperature…1 June 2018

An intravenous delivery protocol for CHA at 0.25mg/(kg·h) that, when coupled with conductive cooling, achievesand maintains a prescribed and consistent target Tb between 32°Cand 34°C for 24 hours.

Physiologicalhyperinsulinemia caused by acute hyperglycemia minimizes renal sodium loss bydirect action on kidneys.

DebraL IrsikM.Brands

Medicine, Biology American Journal of Physiology.Regulatory…  23 May 2018

The hypothesis that meal-induced increases in plasmainsulin are a major component of normal sodium homeostasis, and that thisoccurs by direct action of insulin on the kidney is supported.

The normalincrease in insulin after a meal may be required to prevent postprandial renalsodium and volume losses.

DebraL IrsikB.Blazer-YostA.StaruschenkoM.Brands

Medicine, Biology

American Journal of Physiology. Regulatory…   1 June 2017

It is demonstrated that the normal increase incirculating insulin in response to hyperglycemia may be required to preventexcessive renal sodium and volume losses and suggested that insulin may be a physiologicalregulator of sodium balance.